Scuffham Amps plugin by S-Gear uses continuous controller message (cc) to map parameters. Bome Midi Translator can convert Midi notes and program changes from Looptiumus into CC messages. It also has a scripting language with conditional rules to parse midi events. For example, you can create an On/Off switch to toggle the guitar tuner in Scuffham Amps. Bome is available for Mac and Window.